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7438626 
Journal Article 
Antiarrhythmic Medications 
Gomes, JA; , 
2020 
Springer International Publishing 
Cham 
Heart Rhythm Disorders 
305-333 
Until the advent of ablative therapy and the implantable defibrillator, antiarrhythmic drugs (AADs) were the mainstay in the short- and long-term management of cardiac arrhythmias. In this chapter, the author provides a historical overview of AADs, their classification according to the Singh–Vaughan Williams, and the more recent Sicilian Gambit Classification, the debacle of the CAST study, and details the pharmacotherapy of different classes of AADs and outlines general principles in the use of AADs.