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7438803 
Journal Article 
The Anatomy and Physiology of the Human Stress Response 
Everly, GS; Lating, JM; , 
2019 
Springer New York 
New York, NY 
A Clinical Guide to the Treatment of the Human Stress Response 
19-56 
InBoyle, R.the first chapter, we provided the following working definition of the stress response: “Stress is a physiological response that serves as a mechanism of mediation linking any given stressor to its target-organ effect.” By viewing the phenomenology of stress within the context of a “linking” mechanism, we can answer one of the most critical questions in psychosomatic medicine, that is, through what mechanisms can stressor stimuli, such as life events, lead to disease and dysfunction? The response to that query will be addressed within the next three chapters.