US EPA

7439315 

Journal Article 

Target Organ Toxicity 

Gupta, PK; , 

2020 

Springer International Publishing 

Cham 

Problem Solving Questions in Toxicology: 

83-117 

10.1007/978-3-030-50409-0_7 

http://link.springer.com/10.1007/978-3-030-50409-0_7
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Several target organs such as liver, kidney, lungs, heart, ocular and visual apparatus, skin, reproductive organ, immune system, endocrine systems, etc. play an important role for various functions of the body. Damage to any system may lead to serious consequences. In addition to medicinal risks, liver and kidney damages accompany exposure to synthetic chemicals in the workplace or as environmental pollutants. Still other chemicals that harm the excretory organs are consumed as food contaminants. The vulnerability of the liver, kidney, and other organs to xenobiotic toxicity raises the question as to why such chemicals often display “organ selectivity” when inducing toxicity. This chapter briefly describes the overview, key points, and relevant text that are in the format of problem-solving study questions followed by multiple-choice questions (MCQs) along with their answers.