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7439625 
Journal Article 
Acanthosis Nigricans 
Saleh, M; Muzumdar, R; , 
2021 
Springer International Publishing 
Cham 
Endocrine Conditions in Pediatrics 
113-118 
Acanthosis nigricans (AN) is a common skin condition characterized by velvety hyperpigmented skin, most commonly noted in the intertriginous areas such as the neck and axillae. Clinical recognition of AN is essential because AN is associated with a variety of systemic and metabolic disorders, many of which are characterized by obesity and/or insulin resistance. Children with AN should be screened for diabetes and other comorbidities of obesity. Treatment involves addressing the underlying factors. Weight loss and improvement in insulin sensitivity may result in resolution of AN.