US EPA

7439634 

Journal Article 

Modulation of Hypothalamic-Pituitary-Gonadal (HPG) Axis by Phytotherapy Using Different Delivery Approaches 

Mir, IN; Bhat, IA; , 

2021 

Springer Singapore 

Singapore 

Recent updates in molecular Endocrinology and Reproductive Physiology of Fish 

229-242 

10.1007/978-981-15-8369-8_16 

http://link.springer.com/10.1007/978-981-15-8369-8_16
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Reproduction is arguably the most vital process in animals including fish that is being controlled by the brain through hypothalamic-pituitary-gonadal (HPG) axis. Several bioactive compounds from plants were recognized to be having a great role in promoting a variety of biological activities such as growth, immunomodulation, feed consumption and antioxidant activity or can act as antiviral agents. Moreover, phytochemicals have been used for several hundred years as additions to energize, vitalize and eventually curb the male and female reproductive functions. There can be different approaches to administer the plant-based bioactive compounds such as oral, immersion or injection methods. However, the nanodelivery approach forms an effective way to achieve the delivery to target tissues with less or no impediment. The nanodelivery approach improves the efficiency of targeted delivery of plant-based bioactive compounds. The phytochemicals can also be involved in phenotypic sex manipulations that sometimes become necessary in fisheries and aquaculture. The aim of this chapter is to provide an overview of available studies on the reproductive control via HPG axis along with different phytochemicals and their delivery approaches for reproductive modulation.