US EPA

7446736 

Journal Article 

Reduced Graphene Oxide-Modified Screen-Printed Carbon (rGO-SPCE)-Based Disposable Electrochemical Sensor for Sensitive and Selective Determination of Ethyl Carbamate 

Zhao, X; Zuo, J; Qiu, S; Hu, W; Wang, Y; Zhang, J 

2017 

Yes 

Food Analytical Methods
ISSN: 1936-9751 

Springer New York LLC 

10 

10 

3329-3337 

English 

10.1007/s12161-017-0886-2 

WOS:000409064100014 

Ethyl carbamate (EC), a multi-site genotoxic carcinogen, exists in fermented food and beverages. However, the existing analytical methods need precise instrument, complex sample pretreatment, time-consuming, and high cost. Therefore, a disposable electrochemical biomimetic sensor was developed for fast and selective detection of EC based on reduced graphene oxide/screen-printed carbon composite electrode (rGO/SPCE). Firstly, the SPCE is modified with rGO by electrodeposition process that increased current signal and decreased the impedance of contact interface. Secondly, the OAP/rGO/SPCE biomimetic sensor was synthesized through electropolymerization by cyclic voltammograms in mixed solution of template of EC and monomer of O-aminophenol (OAP). The sensor specifically bound to EC quickly without sample pretreatment. A linear range was from 100 to 1300 nM, and a detection limit of 37 nM was achieved. The detection time is less than 5 min. The sensor possesses advantages include good chemical and mechanical stability, simplicity, low cost of preparation, and sensitive and label-free determination. © 2017, Springer Science+Business Media New York. 

Reduced graphene oxide; Screen-printed carbon electrode; O-aminophenol; Ethyl carbamate; Molecular imprinting