US EPA

7452205 

Journal Article 

Effective Guanidine-Catalyzed Synthesis of Carbonate and Carbamate Derivatives from Propargyl Alcohols in Supercritical Carbon Dioxide 

Della Ca', N; Gabriele, B; Ruffolo, G; Veltri, L; Zanetta, T; Costa, M 

2011 

1 

Advanced Synthesis & Catalysis
ISSN: 1615-4150
EISSN: 1615-4169 

353 

1 

133-146 

English 

10.1002/adsc.201000607 

WOS:000287103200017 

The reactions of propargyl alcohols with carbon dioxide in supercritical carbon dioxide or in acetonitrile with gaseous carbon dioxide in the presence of organic bases as catalysts have been examined. Bicyclic guanidines are effective catalysts for the formation of α-methylene cyclic carbonates under mild reaction conditions. Oxoalkyl carbonates, oxoalkyl carbamates or α-methyleneoxazolidinones are obtained in high yields and good selectivities in one-step starting from propargyl alcohols and an external nucleophile (alcohols or amines) using bicyclic guanidines as catalysts in supercritical carbon dioxide. Propargylic diols under the same reaction conditions underwent a rearrangement process instead of carbon dioxide insertion whereas in the presence of an external nucleophile the formation of oxocarbonates, oxocarbamates or cyclic carbamates was achieved in satisfactory yields. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. 

carbon dioxide fixation; carboxylation; homogeneous catalysis; organocatalysis; supercritical fluids