US EPA

7456884 

Journal Article 

Muscle relaxants in treating tempromandibular joint disorder- an update 

Sharmila, R 

2015 

Pharmainfo Publications 

7 

8 

611-614 

English 

To study about the muscle relaxants are useful in treating the TMJ disorders.Various mechanism behind the muscle relaxants like diazepam,metaxalone,alprazolam,carisprodol and cyclobenzaprine are useful in treating tempromandibular joint disorder.A muscle relaxant is a drug which affects skeletal muscle function and decreases the muscle tone. It may be used to alleviate symptoms such as muscle spasms, pain, and hyper reflexia. The term “muscle relaxant” is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics. The muscle relaxants is used in treating tempromandibular disorder are carisprodol, cyclobenzaprine, diazepam, metaxalone, alprazolam and tizanidine. Diazepam appears to reduce spasticity by enhancing the inhibitory effects of neurotransmitter GABA. It also exerts some supraspinal sedative effect. Diazepam has efficacy in patients with spinal cord injury, hemiplegia, and multiple sclerosis. Carisoprodol is a carbamate derivative. Since, tempromandibular disorder is a common disease, this study is aimed to treat the tempromandibular disorder using the muscle relaxants and bring the overall awearness. © 2015, Pharmainfo Publications. All rights reserved. 

Alprazolam; Carisprodol; Cyclobenzaprine; Diazepam; Hemiplegia and reflexia; Metaxalone; Muscle relaxants; Tempromandibular joint disoder; Tizanidine; 4 aminobutyric acid; alprazolam; baclofen; carisoprodol; cyclobenzaprine; diazepam; metaxalone; muscle relaxant agent; neurotransmitter; tizanidine; Article; hemiplegia; human; multiple sclerosis; spasticity; spinal cord injury; temporomandibular joint disorder