Health & Environmental Research Online (HERO)


Print Feedback Export to File
7489431 
Journal Article 
An improved profess for synthesis of dibenzo-[B,F][1,4]-thiazepine-11-(10H)-one 
Prasad, AVGS; Karunakar, D; Srinivas, B; Prasanna, B 
2013 
0 
International Journal of ChemTech Research
ISSN: 0974-4290 
5 
4 
1902-1905 
English 
A process was developed for synthesis of 2-(phenyl thio)-phenyl carbamate 4 from 2-nitro diphenyl sulphide 1 via., in a single step synthesis of 2-nitro diphenyl sulphide 1 with an aqueous solution of Fe powder and NH4Cl than followed by treated with phenyl chloroformate. The ambient conditions, excellent product yields, easy work up procedure and short reaction time make this synthetic strategy a better protocol for the synthesis of an intermediate 4 and dibenzo[b, f](1,4)-thiazepine-11-(10H)-one 5. The structures of all the compounds were confirmed by their IR, 1H NMR and mass spectral analysis. 
Iron powder; Phenyl cloroformate; Thiazepine and poly phosphoric acid; ammonium chloride; iron; polyphosphate; thiazepine derivative; article; drug synthesis; high performance liquid chromatography; proton nuclear magnetic resonance 
Other
• Harmful Algal Blooms- Health Effects
     April 2021 Literature Search
          Scopus