US EPA

7493745 

Journal Article 

Determination of some carbamate pesticides in human body fluids by headspace solid phase micro extraction and gas chromatography 

Seno, H; Kumazawa, T; Ishii, A; Nishikawa, M; Watanabe, K; Hattori, H; Suzuki, O 

1996 

0 

Japanese Journal of Forensic Toxicology
ISSN: 0915-9606 

14 

3 

199-203 

English 

Headspace solid phase micro extraction (SPME) has been applied to six carbamate pesticides, viz. xylylcarb, XMC, isoprocarb, fenobucarb, propoxur and carbofuran, in human whole blood and urine. Sample solution, after mixing with sodium chloride, was heated in a vial at 70°C, and an SPME fiber was exposed to the headspace of the vial. Immediately after the fiber was pulled out, the fiber needle was injected into the port of a gas chromatograph with a flame ionization detector. Recoveries were 0.582-1.87 % for whole blood, and 2.97-20.6 % for urine; it was highest for fenobucarb and lowest for carbofuran. The detection limits were about 0.1-0.5 μg/ml of whole blood, and 0.01-0.05 μg/ml of urine. ©1996 Japanese Association of Forensic Toxicology. All rights reserved. 

Carbamate pesticides; Carbofuran; Fenobucarb; Gas chromatography; Headspace method; Isoprocarb; Propoxur; Solid phase micro extraction (SPME); XMC; Xylylcarb