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Citation
Tags
HERO ID
7500038
Reference Type
Journal Article
Subtype
Review
Title
Recent Developments and Biological Activities of N-Substituted Carbazole Derivatives: A Review
Author(s)
Bashir, M; Bano, A; Ijaz, AS; Chaudhary, BA
Year
2015
Is Peer Reviewed?
1
Journal
Molecules
ISSN:
1420-3049
Volume
20
Issue
8
Page Numbers
13496-13517
Language
English
PMID
26213906
DOI
10.3390/molecules200813496
Web of Science Id
WOS:000361375400001
Abstract
Carbazoles represent an important class of heterocycles. These have been reported to exhibit diverse biological activities such as antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidative, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective and pancreatic lipase inhibition properties. A series of carbazole derivatives such as N-substituted carbazoles, benzocarbazoles, furocarbazoles, pyrrolocarbazoles, indolocarbazoles, imidazocarbazoles, etc. have been synthesized. The N-substituted derivatives have gained the attention of researchers due to their therapeutic potential against neurological disorders and cell proliferation. Herein an attempt is made to review the medicinal importance of recently synthesized N-substituted carbazoles.
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