US EPA

7530184 

Journal Article 

Impacts of air pollution on dry eye disease among residents in Hangzhou, China: A case-crossover study 

Mo, Zhe; Fu, Q; Lyu, D; Zhang, L; Qin, Z; Tang, Q; Yin, H; Xu, P; Wu, L; Wang, X; Lou, X; Chen, Z; Yao, Ke 

2019 

Yes 

Environmental Pollution
ISSN: 0269-7491
EISSN: 1873-6424 

246 

183-189 

English 

30543944 

10.1016/j.envpol.2018.11.109 

WOS:000458222100022 

The purpose of this study is to investigate the potential associations between air pollution and dry eye disease (DED). Data of outdoor air pollutants and meteorology as well as outpatient visits for DED were collected. A time-stratified case-crossover approach was used to analyze the associations between ambient air pollutants and outpatient visits for DED. Among the 5062 DED patients studied, 65.45% were female and 34.55% were male. In the single-pollutant model, significant associations were observed between an increase of 10 μg/m3 in the concentrations of fine-particulate matter with a median aerometric diameter of less than 10 μm (PM10), fine-particulate matter with a median aerometric diameter of less than 2.5 μm (PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) and outpatient visits for DED. These results were consistent with those of the multipollutant model. The strongest associations between air pollutants and patient visits were observed during the cold season and in patients aged 21-40. The significant association between air pollutants (PM10, PM2.5, SO2, NO2, and CO) and DED outpatient visits indicates the importance of increased environmental protection. 

Air pollution; Dry eye disease; Pollutants; Case-crossover study