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HERO ID
7544222
Reference Type
Journal Article
Title
An Antidote to Parathion Poisoning: Pralidoxime Chloride (Protopam Chloride)
Author(s)
Rosenbaum, EE; Herschler, RJ; Jacob, SW; ,
Year
1965
Is Peer Reviewed?
Yes
Journal
JAMA: Journal of the American Medical Association
ISSN:
0098-7484
EISSN:
1538-3598
Volume
192
Issue
4
Page Numbers
314-315
Language
English
PMID
14271982
DOI
10.1001/jama.1965.03080170042011
Abstract
Pralidoxime chloride is an effective antidote to organophosphate poisoning when it is used with atropine and other supportive measures. At present, it should be used only in cases of acute intoxication and should be given parenterally; its oral or prophylactic use cannot be recommended until further studies are completed. It may also be used as an antagonist to certain carbamate-type anticholinesterases. However, since it is not equally antagonistic to all cholinesterase inhibitors, the possible effectiveness of pralidoxime in counteracting a particular insecticide or drug must be considered individually. © 1965, American Medical Association. All rights reserved.
Keywords
antidote; article; ANTIDOTES; Antidotes
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