Secondary phosphine oxides assisted palladium complexes catalyzed catellani reaction for the formation of carbazole derivatives | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

7548067

Reference Type

Journal Article

Title

Secondary phosphine oxides assisted palladium complexes catalyzed catellani reaction for the formation of carbazole derivatives

Author(s)

Chen, YaC; Chou, HMin; Kao, IH; Chang, YuC; Hong, FE; ,

Year

2017

Is Peer Reviewed?

Yes

Journal

Journal of Organometallic Chemistry
ISSN: 0022-328X
EISSN: 1872-8561

Publisher

ELSEVIER SCIENCE SA

Location

LAUSANNE

Page Numbers

389-396

DOI

10.1016/j.jorganchem.2017.07.018

Web of Science Id

WOS:000407858700049

URL

https://linkinghub.elsevier.com/retrieve/pii/S0022328X17304473
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Abstract

Several secondary phosphine oxides (SPOs, 2a-2d) as well as 2a-chelated palladium complex 2a_Pd were employed in Catellani type reaction for the synthesis of 1-methyl-9H-carbazole (4) from 2-iodotoluene and N-(2-bromophenyl)acetamide (3). The application of these ligands (2a-2d) and palladium complex (2a_Pd) in this reaction is beneficial in terms of increasing the yield of the major product, 4. An elaborated mechanism was proposed to account for the observation of 4 as well as some side products, 5, 6, 7, and 8, via C-C and C-N bonds formation processes. (C) 2017 Published by Elsevier B.V.