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7548122 
Journal Article 
Microwave-induced synthesis of nitrogen-mustard derivatives 
Kidwai, M; Kumar, R; Kohli, S 
1999 
1 
Indian Journal of Chemistry. Section B
ISSN: 0376-4699
EISSN: 0975-0983 
38 
9 
1132-1135 
WOS:000084587700027 
N,N-Bis (2-hydroxyethyl) amino substituted propiophenones 2a-c have been prepared using Mannich reaction from substituted acetophenones la-e 2a-c on hydrazinolysis yield 3a-f which on chlorination give nitrogen mustards 4a-f. 4a-f on reaction with chloracetyl chloride, N-methylmorpholine and chlorobenzene under microwave activation (MWI) afford beta-lactams 5a-f while cyclisation of 4a-f with polyphosphoric acid under MWI give the indoles 6a-f.