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HERO ID
7550427
Reference Type
Journal Article
Title
Synthesis and Cytotoxicity of Nitrogen Mustard/Tripolypyrrole Conjugate
Author(s)
Ye, Y; Liu, CJ; Liu, YH; Cao, LF; Zhao, YF
Year
2008
Is Peer Reviewed?
Yes
Journal
Journal of Heterocyclic Chemistry
ISSN:
0022-152X
Volume
45
Issue
6
Page Numbers
1851-1854
Web of Science Id
WOS:000261077600047
URL
http://
://WOS:000261077600047
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Abstract
A series of nitrogen mustard derivatives were synthesized by chloroform reaction and coupling reaction using DCC/HOBT as promoting additives. The structure of compound was confirmed by (1)H NMR, (31)P NMR, MS and IR. The data show that the nitrogen mustard with tripolypyrrole as the linker inhibits all the four tested cells and has the highest activity.
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