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Technical Report 
EPA Report 
Evaluation of the carcinogenicity of ethylene oxide: External review draft 
U.S. Environmental Protection Agency :: U.S. EPA 
U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment 
Washington, DC 
EPA conducted a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of ethylene oxide (cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database. Ethylene Oxide is a gas at room temperature used in chemical manufacturing and as a sterilizing agent for medical equipment and a fumigating agent for spices. Human exposure occurs in occupations involving contact with the gas in production facilities and hospitals that sterilize medical equipment. EtO can also be inhaled by residents living near production or sterilizing/fumigating facilities.