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7558060 
Journal Article 
Transition metal complexes in organic synthesis, part 74: Total synthesis of the marine alkaloid 6-chlorohyellazole 
Knolker, HJ; Frohner, W; Heinrich, R; , 
2004 
1 
Synlett
ISSN: 0936-5214
EISSN: 1437-2096 
GEORG THIEME VERLAG KG 
STUTTGART 
2705-2708 
WOS:000225654700009 
A considerably improved iron-mediated synthesis leads to the marine carbazole alkaloid hyellazole on large scale in eight steps and 63% overall yield from 2,6-dimethoxytoluene. The first conversion of hyellazole into 6-chlorohyellazole has been achieved along with remarkably regiospecific halogenation reactions.