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HERO ID
7558659
Reference Type
Journal Article
Title
Photochemical studies of the anti-inflammatory drug diclofenac in aqueous solutions
Author(s)
Koutsouba, P; Dasenakis, M; Hiskia, A; Tsipi, D; ,
Year
2001
Publisher
UNIV AEGEAN
Location
ATHENS
Page Numbers
234-241
Web of Science Id
WOS:000175781000034
Abstract
Scientists all over the world present data confirming that a wide variety of drugs and their metabolites are showing up in the aquatic environment, In Greece, diclofenac an antiflammatory drug was detected in every sample collected from the effluents from several sewage treatment plants. In this work photodegradation of diclofenac was studied, after irradiation with sunlight and UV light in aqueous solutions. Diclofenac degraded completely after irradiation and a number of breakdown products was detected by HPLC-DAD. The identification of three photoproducts, 8-chlorocarbazole-1-acetic acid, 8-hydroxycarbazole-1-acetic acid and carbazole-1-acetic acid was achieved by GC-MS, after derivatization with BSTFA.
Editor(s)
Lekkas, TD;
ISBN
*************
Conference Name
7th International Conference on Environmental Science and Technology
Conference Location
ERMOUPOLIS, GREECE
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