Health & Environmental Research Online (HERO)


Print Feedback Export to File
7564816 
Journal Article 
[Efficacy of taurine haloamines and chlorhexidine against selected oral microbiome species] 
Pasich, E; Bialecka, A; Marcinkiewicz, J; , 
2013 
0 
Medycyna Doświadczalna i Mikrobiologia
ISSN: 0025-8601
EISSN: 2545-2517 
65 
3 
187-196 
Polish 
24432558 
Uncontrolled bacteria of dental plaque generate formation of oral biofilm located on teeth and subgingival surfaces. It may induce local inflammation (gingivitis) with further development of periodontal diseases. A variety of oral bacteria such as Streptococcus mutans and Porhyromonas gingivalis are involved in pathogenesis of dental carries and periodontitis. Very often bacterial infections are associated with candidiasis (Candida albicans). Chlorhexidine (CHX) is the most commonly used antiseptic in dentistry due to its strong antibacterial activity and capacity to reduce the accumulation of oral biofilms. However, other antiseptics, especially endodontic irrigants, are still tested to improve their preventive and therapeutic effects in oral cavity infections. In this in vitro study we have compared antimicrobial activity of CHX with that of taurine chloramine (TauC1) and taurine bromamine (TauBr), natural taurine derivatives with known antibacterial and anti-inflammatory properties.