Synthesis of N,N-didemethylzolpidem-N-{2-{3-(4-hydroxy-3- I-125 iodophenyl)}methyl propionate} for use in radioimmunoassay | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

7569575

Reference Type

Journal Article

Title

Synthesis of N,N-didemethylzolpidem-N-{2-{3-(4-hydroxy-3- I-125 iodophenyl)}methyl propionate} for use in radioimmunoassay

Author(s)

Declerck, I; Daenens, P

Year

1997

Is Peer Reviewed?

Yes

Journal

Journal of Labelled Compounds and Radiopharmaceuticals
ISSN: 0362-4803
EISSN: 1099-1344

Volume

Issue

Page Numbers

195-203

DOI

10.1002/(sici)1099-1344(199703)39:3<195::Aid-jlcr958>3.0.Co;2-8

Web of Science Id

WOS:A1997WL16600002

URL

http://://WOS:A1997WL16600002
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Abstract

The I-125-derivative of zolpidem was prepared by iodination of a L-tyrosine methyl ester conjugate of a zolpidem precursor. The iodinated compound has been used as purified by normal phase HPLC, in combination with gamma counting detection. The structure was confirmed by high resolution L-SIMS.