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7580619 
Journal Article 
Syntheses of 2-formyl-, 2,3-diformyl- and 8-formyl-1-azaazulenes 
Koizumi, K; Miyake, C; Ariyoshi, T; Umeda, K; Yamauchi, N; Tagashira, S; Murakami, Y; Fujii, H; Abe, N 
2007 
Yes 
Heterocycles
ISSN: 0385-5414 
73 
1 
325-+ 
WOS:000253154500027 
2-Styryl-1-azaazulenes were synthesized by two ways: a) Suzuki coupling of 2-bromo-1-azaazulenes with trans-2-phenylvinylboronic acid b) Condensation of 2-methyl-1-azaazulene, being synthesized by Negishi coupling of 2-bromo-1-azaazulene with dimethylzinc, with benzaldehyde. Oxidative cleavage of 2-styryi-1-azaazulenes with OsO4-KIO4 gave 2-formyl-1-azaazulenes. 8-Formyl-1-azaazulenes were synthesized by the reaction of 1-azaazulenes with 2-lithio- 1,3-dithiane followed by the hydrolysis.