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7606803 
Journal Article 
Effects of culture conditions on dibenzofuran production by cultured mycobionts of lichens 
Kon, Y; Kashiwadani, H; Wardlaw, JH; Elix, JA; , 
1997 
1 
Symbiosis
ISSN: 0334-5114 
INT SCIENCE SERVICES/BALABAN PUBLISHERS 
REHOVOT 
23 
2-3 
97-106 
English 
WOS:A1997YL66000001 
Two dibenzofurans, isostrepsilic acid and hypostrepsilic acid, were produced in large quantities by the mycobiont of Usnea orientalis cultured on a malt-yeast extract medium containing sugar alcohols. The natural lichen growing in the field produces usnic and salazinic acid but not the above dibenzofurans. Isostrepsilic acid is a new product which has shown to be 3,7-dihydroxy-9-hydroxymethyl-1-methydibenzofuran-2-carboxylic acid. It seems that the production of these compounds is probably due to the combined effects of the high osmotic pressure of the medium and the nutritional conditions. The production of the dibenzofurans was markedly repressed by actively photosynthesizing photobionts. 
Dibenzofuran; Hypostrepsilic acid; Isostrepsilic acid; Lichen mycobiont; Lichens 
3rd International Lichenological Symposium (IAL3) 
SALZBURG, AUSTRIA