US EPA

7626686 

Journal Article 

Perturbation of the PET process in fluorophore-spacer-receptor systems through structural modification: transition metal induced fluorescence enhancement and selectivity 

Bag, B; Bharadwaj, PK; , 

2005 

Yes 

Journal of Physical Chemistry B
ISSN: 1520-6106
EISSN: 1520-5207 

AMER CHEMICAL SOC 

WASHINGTON 

109 

10 

4377-4390 

English 

16851506 

10.1021/jp047557b 

WOS:000227629700014 

https://pubs.acs.org/doi/10.1021/jp047557b
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Several fluorescent signaling systems are built in the format fluorophore-spacer-receptor with ethylenediamine or N,N-dimethylethylenediamine as the receptor, anthracene as the fluorophore, and a methylene group as the spacer. The receptors are derivatized with different electron-withdrawing groups such as 4-nitrobenzene, 4-nitro-2-pyridine, and 2,4-dinitrobenzene, to perturb the photoinduced intramolecular electron transfer (PET) process from the nitrogen lone-pair to the fluorophore. The photophysical properties of these supramolecular systems and their fluorescence responses toward a number of quenching transition metal ions are reported. It is shown that the PET is highly efficient in the absence of a metal ion. With a metal ion input, the fluorescence can be recovered to a different extent depending on the nature of the metal and on the overall architecture of the system as well. Despite the possibility of strong interaction between the fluorophore and the metal ion, significant fluorescence enhancement is observed with quenching of paramagnetic transition metal ions. The complex stability data show that the stability constants for the metal ions showing fluorescence enhancement are of the order of 10(4) M(-1). This study shows that structurally simple fluorescent signaling systems for quenching transition metal ions can be built by maximizing the PET. It is also shown here that simple structural modification can make these systems highly specific for particular transition metal ions for potential applications in several contemporary areas of research.