Synthesis of 2-mono- and 2,7-disubstituted-1,8-dihydroxy-9-anthrones, a novel member of the anthrone class of antipsoriatic agents | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

7628896

Reference Type

Journal Article

Title

Synthesis of 2-mono- and 2,7-disubstituted-1,8-dihydroxy-9-anthrones, a novel member of the anthrone class of antipsoriatic agents

Author(s)

Sharghi, H; Tamaddon, F; ,

Year

1998

Publisher

SHIRAZ UNIV

Location

SHIRAZ

Page Numbers

431-437

Web of Science Id

WOS:000077060200003

Abstract

The synthesis of 1,8-dihydroxy-2-(prop-2'-enyl) 9-anthrone (4), 1,8-dihydroxy-2,7-bis(prop-2'-enyl) 9-anthrone (6) and 1,8-dihydroxy-2-(prop-1-enyl)-7-propyl-9-anthrone (8), a new class of anthracene derivatives of potential pharmacological interest is described, involving reductive Claisen rearrangement of 1,8-bis(prop-2'-enyloxy) anthraquinone (3) with tin and hydrochloric acid in acetic acid.