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7641957 
Journal Article 
First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution 
Ojida, A; Mito-Oka, Y; Inoue, MA; Hamachi, I 
2002 
Yes 
Journal of the American Chemical Society
ISSN: 0002-7863
EISSN: 1520-5126 
124 
22 
6256-6258 
English 
12033851 
The first fluorescent chemosensors toward a native phosphorylated peptide are successfully synthesized. Dinuclear zinc(II)-dipicolylamine-based anthracene (1, 2) can selectively recognize and sense phosphorylated species with an increase in the fluorescence intensity. We also demonstrated that these artificial receptors fluorometrically detect a phosphorylated peptide with high affinity (>107 M-1) in aqueous solution.