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7664509 
Journal Article 
A DNA mimic made of non-nucleosidic phenanthrene building blocks 
Langenegger, SM; Häner, R; , 
2005 
Yes 
ChemBiochem
ISSN: 1439-4227
EISSN: 1439-7633 
WILEY-V C H VERLAG GMBH 
WEINHEIM 
6 
12 
2149-2152 
English 
16270366 
WOS:000233916600004 
(Figure Presented) Stable stacking. DNA mimics have been prepared from simple, non-nucleosidic building blocks. These oligonucleotides, which contain extended stretches of phenanthrene derivatives, form stable hybrids. The phenanthrene residues contribute to the stability of the duplex through interstrand stacking interactions. The hybrids adopt an overall B-form structure, thus mimicking natural DNA. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA. 
DNA; Non-nucleosidic base surrogates; Oligonucleotides; Phenanthrene; Stacking interactions