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HERO ID
7665797
Reference Type
Journal Article
Title
Total synthesis of laetevirenol A
Author(s)
Choi, YL; Kim, BT; Heo, JN; ,
Year
2012
Is Peer Reviewed?
Yes
Journal
Journal of Organic Chemistry
ISSN:
0022-3263
EISSN:
1520-6904
Publisher
AMER CHEMICAL SOC
Location
WASHINGTON
Volume
77
Issue
19
Page Numbers
8762-8767
Language
English
PMID
22946550
DOI
10.1021/jo301345a
Web of Science Id
WOS:000313767800042
URL
https://pubs.acs.org/doi/10.1021/jo301345a
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Abstract
The first complete synthesis of laetevirenol A was performed in nine steps via intramolecular Friedel-Crafts alkylation in a trans-selective manner. The key phenanthrene intermediate was synthesized by a one-pot Suzuki-Miyaura coupling and an aldol condensation cascade reaction.
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