Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
7670142
Reference Type
Journal Article
Title
Effects of Fructus schizandrae on cycloheximide-induced amnesia in rats
Author(s)
Hsieh, MT; Tsai, ML; Peng, WH; Wu, CR
Year
1999
Is Peer Reviewed?
1
Journal
Phytotherapy Research
ISSN:
0951-418X
EISSN:
1099-1573
Volume
13
Issue
3
Page Numbers
256-257
Language
English
PMID
10353174
DOI
10.1002/(SICI)1099-1573(199905)13:3<256::AID-PTR435>3.0.CO;2-H
Web of Science Id
WOS:000080405700022
Abstract
The effects of Fructus Schisandrae (Schizandra Chinensis, (FS) on cycloheximide (CXM)-induced amnesia by using a passive avoidance task were studied in rats. FS at 0.25 and 0.75 g/kg administered for 1 week significantly prolonged the CXM-shortened step-through latency (STL). Of the fractions (n-hexane, chloroform and water), only the water fraction at 25 mg/kg administered for 1 week prolonged the CXM-shortened STL. These results suggest that the water fraction is the main active fraction of FS.
Keywords
Fructus schizandrae; schizandra chinensis; passive avoidance task; cycloheximide
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity