Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific biomarker for acute coronary syndrome--comparison with other biomarkers | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

7685852

Reference Type

Journal Article

Title

Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific biomarker for acute coronary syndrome--comparison with other biomarkers

Author(s)

Kume, N; Mitsuoka, H; Hayashida, K; Tanaka, M; Kominami, G; Kita, T; ,

Year

2010

Is Peer Reviewed?

Yes

Journal

Journal of Cardiology
ISSN: 0914-5087

Publisher

ELSEVIER

Location

AMSTERDAM

Volume

Issue

Page Numbers

159-165

Language

English

PMID

20605699

DOI

10.1016/j.jjcc.2010.05.002

Web of Science Id

WOS:000281929300006

URL

https://linkinghub.elsevier.com/retrieve/pii/S0914508710000948
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Abstract

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) appears to be involved in atherosclerotic plaque vulnerability and rupture. Circulating soluble LOX-1 (sLOX-1) levels are dramatically elevated in patients with acute coronary syndrome (ACS), and its diagnostic sensitivity and specificity is superior to high-sensitivity C-reactive protein (hs-CRP). In this study, we have compared the diagnostic value of sLOX-1 for ACS with those of troponin T (TnT) and heart-type fatty acid binding protein (H-FABP).

Keywords

Atherosclerosis; Coronary artery disease; Diagnostic techniques; Troponin; Unstable angina