Lipase-mediated dynamic kinetic resolution (DKR) of secondary alcohols in the presence of zeolite using an ionic liquid solvent system | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

7695329

Reference Type

Journal Article

Title

Lipase-mediated dynamic kinetic resolution (DKR) of secondary alcohols in the presence of zeolite using an ionic liquid solvent system

Author(s)

Shimomura, K; Harami, H; Matsubara, Yui; Nokami, T; Katada, N; Itoh, T; ,

Year

2015

Is Peer Reviewed?

Yes

Journal

Catalysis Today
ISSN: 0920-5861

Publisher

ELSEVIER

Location

AMSTERDAM

Volume

255

Page Numbers

41-48

Language

English

DOI

10.1016/j.cattod.2014.10.052

Web of Science Id

WOS:000358388000008

URL

https://linkinghub.elsevier.com/retrieve/pii/S0920586114007913
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Abstract

Transition metal free dynamic kinetic resolution (DKR) of 1-phenyethanol and 2,3-dihydro-1H-inden-1-ol has been accomplished by the combination of Candida antarctica lipase (CAL-B) and zeolite using vinyl octanoate or p-chlorophenyl pentanoate as acyl donor in a mixed solvent system of ionic liquid and hexane in the presence of 1.0eq. of water. Duplicated use of the catalysts has also been demonstrated in the DKR of 2,3-dihydro-1H-inden-1-ol using this reaction system. (C) 2014 Elsevier B.V. All rights reserved.

Keywords

Dynamic kinetic resolution; Ionic liquids secondary alcohols; Lipase; Zeolite