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7719624 
Journal Article 
Review 
Regenerative Medicine Strategies for Esophageal Repair 
Londono, R; Badylak, SF 
2015 
1 
Tissue Engineering, Part B: Reviews
ISSN: 1937-3368 
21 
4 
393-410 
English 
25813694 
WOS:000363890300006 
Pathologies that involve the structure and/or function of the esophagus can be life-threatening. The esophagus is a complex organ comprising nonredundant tissue that does not have the ability to regenerate. Currently available interventions for esophageal pathology have limited success and are typically associated with significant morbidity. Hence, there is currently an unmet clinical need for effective methods of esophageal repair. The present article presents a review of esophageal disease along with the anatomic and functional consequences of each pathologic process, the shortcomings associated with currently available therapies, and the latest advancements in the field of regenerative medicine with respect to strategies for esophageal repair from benchtop to bedside.