Health & Environmental Research Online (HERO)


Print Feedback Export to File
7736347 
Journal Article 
A study of neem leaves: Identification of method and solvent in extraction 
Hashim, N; Abdullah, S; Hassan, LS; Ghazali, SR; Jalil, R 
2021 
1 
Materials Today: Proceedings
ISSN: 2214-7853 
Elsevier Ltd 
5th International Conference of Chemical Engineering and Industrial Biotechnology, ICCEIB 2020 
42 
217-221 
English 
WOS:000635638700034 
The efficiency of Azadirachta indica (neem leaves) to be used in medicine and consumer products is proven due to the bioactive compounds contains in the plant. The most effective solvent needs to explore to optimize the extract yield. In this study, two methods of extraction were applied, Soxhlet, and immersion techniques to study which method gives higher neem extract. Different solvents were used as an extraction medium, methanol, ethanol, ethyl acetate, and hexane. The physical properties and stability tests were observed after week 4 and week 8. The yield percentages collected from both methods were recorded. All crude oil of extract gave brown color and smelly with high viscosity of the solution. The sedimentation collected was less than 2 w/w% after 1500 rpm of centrifuging speed and 5 w/w% after 3000 rpm of speed. The pH study showed all extracts gave low acidic after week 4 (5.6-5.9) and became neutral after week 8 (7.0-7.2) to determine the stability of the extract. The maximum percentage of yield, 22.0% obtained from ethanol extraction in the immersion method and 21.5% from Soxhlet extraction, suggested ethanol enhanced the extract production. Distilled water was used in the immersion method to study the potential of the solvent since it is cost-effective and environmentally friendly. The extracted amount was lower than obtained from other solvents and the maximum yield attained from extraction at 90 °C. As conclusion, ethanol gave maximum yield at 90 °C of extraction. © 2019 Elsevier Ltd. All rights reserved. 
Neem leaves; Soxhlet extraction; Solvent; Bioactive compound; Stability 
Setiabudi H.D.