Health & Environmental Research Online (HERO)


Print Feedback Export to File
7737140 
Journal Article 
In Vitro Antileishmanial Activity and GC-MS Analysis of Whole Plant Hexane Fraction of Achillea wilhelmsii (WHFAW) 
Achakzai, JK; Panezai, MA; Kakar, AM; Akhtar, B; Akbar, Ali; Kakar, S; Khan, J; Khan, NY; Khan, GM; Baloch, N; Khoso, M; Panezai, M 
2019 
Yes 
Journal of Chemistry
ISSN: 2090-9063
EISSN: 2090-9071 
Hindawi Limited 
2019 
English 
WOS:000491925700001 
In this study, GC-MS analysis has shown that whole plant hexane fraction of Achillea wilhelmsii (WHFAW) consists of 66 compounds which exhibited antileishmanial activity. Antileishmanial bioassay was the method used for determining antileishmanial activity. The inhibitory concentration (IC50) which was observed for whole plant hexane fraction of Achillea wilhelmsii (WHFAW) against parasitic and vector-borne disease, leishmaniasis, is 58.27 ± 0.52 μg/mL. For leishmanicidal assay, Leishmania major is the species used for analysis. Whole plant methanol extract of Achillea wilhelmsii (WMEAW) and whole plant aqueous fraction of Achillea wilhelmsii (WAFAW) exhibited no antileishmanial activity. © 2019 Jahangir Khan Achakzai et al.