Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
7741954
Reference Type
Journal Article
Title
Isolation and Purification of Two Triterpenoids from the Chinese Medicinal Plant Fomes officinalis ames
Author(s)
Zhang, H; Feng, Bo; Liu, Ke; Guo, S
Year
2013
Is Peer Reviewed?
Yes
Journal
Asian Journal of Chemistry
ISSN:
0970-7077
EISSN:
0975-427X
Publisher
Chemical Publishing Co.
Location
SAHIBABAD
Volume
25
Issue
11
Page Numbers
6130-6132
Language
English
DOI
10.14233/ajchem.2013.14285
Web of Science Id
WOS:000325089600058
Abstract
A high-speed counter-current chromatography method is developed for the separation and purification of two triterpenoids from the Chinese Uyghur medicinal plant Fomes officinalis ames. Crude triterpenoids were obtained from Fomes officinalis ames through ethanol extraction. Preparative high-speed counter-current chromatography with two-phase solvent systems made up of n-hexane-ethylacetatemethanol-water with a volume ratio of 1:1.5:1.2:1 (v/v) was successfully performed in a stepwise elution. The process yielded two relatively pure triterpenoids in a single run from 500 mg crude extract. The purities of the dehydrosulphurenic acid and 3-ketodehydrosulphurenic acid were 96.8 % and 92.3 %, respectively.
Keywords
Fomes officinalis ames; Counter-current chromatography; Triterpenoids; Preparative chromatography
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity