US EPA

7742439 

Journal Article 

Synthesis of Chiral Polymer by Mukaiyama Aldol Polymerization and its Characterization 

Hazarika, S; Dutta, S; Rao, PG 

2008 

Yes 

Journal of Polymer Materials
ISSN: 0970-0838 

PRINTS PUBLICATIONS PVT LTD 

NEW DELHI 

25 

3 

479-490 

English 

WOS:000263143300013 

In this paper we have reported the synthesis of chiral polymer by asymmetric aldol polymerization of bis(silyl enol ether) and dialdehyde by Mukaiyama aldol reaction which is one of the most important aldol reaction for chiral polymer synthesis. We have studied the polymerization reaction in two different catalytic conditions such as by using a chiral catalyst viz. 1, V′-binaphthyl-2,′ -diol (BINOL) which is modified by reacting it with diethyl zinc solution in hexane. Another catalyst used for the polymerization reaction is lipase, which is a triacylglycerol hydro lases; EC 3.1.1.3. belongs to a most popular group of enzyme and are used for chiral synthesis. A comparative study has also been made for the polymerization reaction in both the catalytic systems. The results obtained in various reaction conditions by changing amount of catalyst, monomer ratio etc. has also been discussed. The polymers were characterized by IR, NMR, GPC, TGA-DTA, specific rotation and circular dichrosm study and it was found that both catalytic conditions give the chiral polymer of approximately same enatioselectivity. © MD Publications Pvt. Ltd. 

Mukaiyarma aldol reaction; BINOL; lipase; circular dichroism