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7744030 
Journal Article 
Enantioselective acylation of 2-hydroxymethyl-2,3-dihydrobenzofurans catalysed by lipase from Pseudomonas cepacia (Amano PS) and total stereoselective synthesis of (-)-(R)-MEM-protected arthrographol 
Ramadas, S; Krupadanam, GLD 
2000 
1 
Tetrahedron: Asymmetry
ISSN: 0957-4166 
PERGAMON-ELSEVIER SCIENCE LTD 
OXFORD 
11 
16 
3375-3393 
English 
WOS:000089843700017 
Lipase Amano PS catalysed acylation of (±)-2-hydroxymethyl-2,3-dihydrobenzofurans using vinyl acetate as the acyl donor in n-hexane gave (-)-(R)-2-acetoxymethyl-2,3-dihydrobenzofurans and (+)-(S)-2-hydroxymethyl-2,3-dihydrobenzofurans in high enantiomeric excess. (-)-(R)-Acetate 18j is converted to (-)-(R)-MEM-protected arthrographol 22. Copyright (C) 2000 Elsevier Science Ltd.