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7744193 
Journal Article 
Polyphenol extraction from mangosteen (Garcinia mangostana Linn) pericarp by bio-based solvents 
Sungpud, C; Panpipat, W; Sae-Yoon, A; Chaijan, M 
2020 
International Food Research Journal
ISSN: 1985-4668 
Universiti Putra Malaysia 
27 
111-120 
English 
Mangosteen pericarp (MP), an abundant agro-food waste in Thailand, can be used to produce polyphenols. In the present work, the effects of bio-based solvents (virgin coconut oil, VCO; propylene glycol, PG; glycerol, and water) in comparison with organic solvents (ethanol and hexane) on extraction and in vitro bioactivities of phenolic compounds from MP were evaluated. Solvents strongly influenced the total phenolic content (TPC), total flavonoid content (TFC), phenolic profiles, antioxidant activity, antibacterial activity, and antidiabetic activity of the extracts. Overall, α-mangostin and-mangostin were the major phenolic constituents found in all extracts. PG was the optimal solvent yielding the highest TPC and TFC with a broad spectrum of phenolic profiles and rendering the extract with the highest antioxidant activity, antibacterial activity, and antidiabetic activity. However, the antibacterial activity of the extract was enhanced when VCO was used. Thus, bio-based solvents, particularly PG, were suitable for the recovery of active phenolic compounds form MP. © 2020, Universiti Putra Malaysia. 
bio-based solvent; mangosteen pericarp; phenolic compound; antioxidant activity; in vitro bioactivities