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7744855 
Journal Article 
The Activity of Rhizomuchor miehei Lipase as a Biocatalyst in Enzymatic Acylation of Cyclic Alcohol 
Iftitah, ED; Srihardyastuti, A; Ariefin, M; AIP 
2017 
Yes 
AIP Conference Proceedings
ISSN: 0094-243X
EISSN: 1551-7616 
American Institute of Physics Inc. 
AIP Conference Proceedings 
1823 
English 
WOS:000404123700117 
We report the activity of Rhizomuchor miehei lipase (RML) as a biocatalyst, in particular the investigations concerning the effort of substrate-structure reactivity on the enzymatic acylation. The acylation was studied using acetic anhydride as an acyl donor and performed in n-hexane as a solvent. The selectivity of the enzymatic acylation was revealed by Gas Chromatography-Mass Spectra. We observed that, RML has shown different behavior when catalyzing the acylation of isopulegol and mixture of isopulegol and citronellal (ratio 1:1). The chemoselectivity for the O-acylation was improved when the acyl acceptor included mixture of isopulegol and citronellal. © 2017 Author(s). 
Purwiandono G.