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7745108 
Journal Article 
Antimicrobial activity of methanol extract and fractions from Sarcochlamys pulcherrima 
Mazumder, AH; Das, J; Gogoi, HK; Chattopadhyay, P; Paul, SB 
2014 
Yes 
Bangladesh Journal of Pharmacology
ISSN: 1991-007X
EISSN: 1991-0088 
9 
1 
4-9 
English 
WOS:000333341600002 
Antimicrobial evaluation of methanol extract of Sarcochlamys pulcherrima leaf and its hexane, ethyl acetate, n-butanol and water fractions against 31 strains of microorganisms, using agar well, agar disc diffusion, and broth microdilu-tion methods, revealed the activity of methanol extract against Trichophyton mentagrophytes, Candida albicans, Staphylococcus aureus and Escheracia coli (zone of inhibition: 21-40 mm, 200 mg/mL, and MIC: 6.25-50 mg/mL). All fractions also displayed antimicrobial activity (5-20 mg/mL), indeed ethyl acetate and n -butanol fractions showed better activity (MIC: 0.156 to 2.5 mg/mL). C. albicans was most sensitive to n-butanol fraction (15 mm, 2.5 mg/mL). Ethyl acetate and n-butanol fractions were more active against T. mentagrophytes (12 mm at 1.25 mg/mL) and S. aureus (ethyl acetate-16 mm, n-butanol-14 mm at 0.625 mg/mL). E. coli was inhibited by n-butanol fraction (13 mm at 2.5 mg/ mL). Further, n-butanol fraction (400 μg/disc) exhibited promising activity against 14 bacteria, 2 dermatophytes and 2 yeasts strains. 
Antimicrobial activity; n-Butanol fraction; Sarcochlamys pulcherrima