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7762019 
Journal Article 
Review 
Therapeutic opportunities of edible antiviral plants for COVID-19 
Patel, B; Sharma, S; Nair, N; Majeed, J; Goyal, RK; Dhobi, M 
2021 
Molecular and Cellular Biochemistry
ISSN: 0300-8177
EISSN: 1573-4919 
476 
2345-2364 
English 
The pandemic of Serious Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) that produces corona virus disease (COVID-19) has challenged the entire mankind by rapidly spreading globally in 210 countries affecting over 25 million people and about 1 million deaths worldwide. It continues to spread, afflicting the health system globally. So far there is no remedy for the ailment and the available antiviral regimens have been unsatisfactory for the clinical outcomes and the mode of treatment has been mainly supportive for the prevention of COVID-19-induced morbidity and mortality. From the time immortal the traditional plant-based ethno-medicines have provided the leads for the treatment of infectious diseases. Phytopharmaceuticals have provided potential and less toxic antiviral drugs as compared to conventional modern therapeutics which are associated with severe toxicities. The ethnopharmacological knowledge about plants has provided food supplements and nutraceuticals as a promise for prevention and treatment of the current pandemic. In this review article, we have attempted to comprehend the information about the edible medicinal plant materials with potential antiviral activity specifically against RNA virus which additionally possess property to improve immunity along with external and internal respiration and exhibit anti-inflammatory properties for the prevention and treatment of the disease. This will open an arena for the development of novel nutraceutical herbal formulations as an alternative therapy that can be used for the prevention and treatment of COVID-19. 
Antiviral Agents pharmacology; Antiviral Agents therapeutic use; COVID-19 drug therapy; COVID-19 etiology; Ethnopharmacology methods; Host-Pathogen Interactions drug effects; Humans; Plants; Edible chemistry; Plants; Medicinal chemistry; SARS-CoV-2 chemistry; SARS-CoV-2 drug effects; SARS-CoV-2 pathogenicity; SARS-CoV-2 physiology; Severe Acute Respiratory Syndrome drug therapy; Virus Internalization drug effects; Virus Replication drug effects; Virus Replication physiology; Index Medicus