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7913294 
Journal Article 
Environmentally Benign Synthesis of 4-Thiazolidinone Derivatives Using a Co/Al Hydrotalcite as Heterogeneous Catalyst 
Subhedar, DD; Yadav, PA; Pawar, SR; Bhanage, BM 
2021 
Yes 
Catalysis Letters
ISSN: 1011-372X
EISSN: 1572-879X 
Springer 
151 
6 
1776-1787 
English 
WOS:000583111500001 
Abstract: The present effort describes facile and environmentally benign synthesis of 4-thiazolidinone via oxidative cyclocondensation of benzyl alcohols, various substituted aromatic anilines and thioglycolic acid using a Co-Al hydrotalcite based heterogeneous catalyst (Co@HT) in methanol act as a solvent. We have synthesized three types of Co@HT with different molar ratio Co@HT-2 (1:1), Co@HT-3 (2:1), Co@HT-4 (3:1). Characterization of synthesized Co@HT catalyst using various analysis techniques such as FT-IR, powder XRD, SEM, XPS, EDS, DTG-TGA and N2 physical adsorption. Among the synthesized hydrotalcite, Co-HT-3 exhibit admirable catalytic activity towards oxidation of benzyl alcohol followed by cyclocondensation of respective aldehydes, anilines and thioglycolic acid into the corresponding 4-thiazolidinones in methanol at 60 οC using O2 as a oxidant. Furthermore, after end of the reaction, the catalyst is easily recovered and eco-friendly without any considerable loss in its catalytic efficiency. Graphic Abstract: [Figure not available: see fulltext.] © 2020, Springer Science+Business Media, LLC, part of Springer Nature. 
Environmentally benign; Heterogeneous; Co/Al Hydrotalcite; Multicomponent; reactions; 4-Thiazolidinones