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791490 
Journal Article 
Subchronic effects of a mixture of persistent chemicals found in the Great Lakes 
Cote, MG; Plaa, GL; Valli, VE; Villeneuve, DC 
1985 
Yes 
Bulletin of Environmental Contamination and Toxicology
ISSN: 0007-4861
EISSN: 1432-0800 
34 
2 
285-290 
Mixts. of 15 persistent chems. [aldrin (I) [309-00-2], dieldrin [60-57-1], DDT [50-29-3], etc.] were well tolerated by both male and female rats when consumed for 91 days at 1-1000 times the water quality objectives proposed for control of persistent chems. found in the Great Lakes. No dose-related toxicol. changes were noted. Although food consumption was significantly lower for the females during week 12, body wt. was not significantly affected. Male rats exhibited no such change. Thus, when several important contaminants were tested in combination at their water quality objectives and even at levels several orders of magnitude higher, they were devoid of toxic consequences. 
Water Resources Abstracts; Great Lakes; Organic compounds; Toxicity; Standards; Dieldrin; Heptachlor; Lindane; Methoxychlor; Toxaphene; Arochlor; Dibutylphthalate; Chlordane; Sublethal effects