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7918224 
Journal Article 
Chiral arene ruthenium complexes .2. A diastereoselective route to [(eta(6)-benzyl alcohol)(COD)Ru] complexes 
Bodes, G; Heinemann, F; Zenneck, U 
1997 
1 
Chemische Berichte
ISSN: 0009-2940 
130 
9 
1321-1325 
English 
WOS:A1997XU67400021 
Two preparative routes are reported that give access to the racemic series of planar chiral [(arenej(COD)Ru] derivatives containing r|6-bonded o-tolyl ketone or aldehyde arene units. The ketone and aldehyde functions of these have subsequently been reduced by nBuLi and PhLi, respectively. Hydrolysis converts the initially formed lithium salts into diastereomeric benzyl alcohol complexes in high yields. The formation of the new stereogenic centre is diastereoselective (88% de) for the aldehyde and diastereospecific for the ketone (de > 99%). Due to a sterically overcrowded situation, the rotation of the chiral side chain of [(COD)(η6-o-tolyl-text-butylphenylmethanol) Ru] (7) is hindered, as is the rotation of the phenyl and text-butyl substituents. As a consequence, the hydroxyl group is fixed at a position close to the metal both in solution and in the solid state. © VCH Verlagsgcscllschaft mbH,. 
arene complexes; ruthenium; diastereoselective; reduction