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7949019 
Journal Article 
High selective autocatalytic esterification of glutamic acid by benzyl alcohol with CuCl2 promoting 
Ma, Y; Li, Z; Su, K; Cheng, B 
2014 
Yes 
Catalysis Communications
ISSN: 1566-7367 
Elsevier B.V. 
48 
15-18 
English 
WOS:000333999200004 
We found that the esterification of l-glutamic acid by benzyl alcohol is greatly promoted by CuCl2 even in H2O solvent, and the selectivity and yield of γ-benzyl ester of l-glutamic acid achieved 100% and 95.31%. Metal cation coordination to the amino acids via neighboring amino and carbonyl groups increased α position carboxyl acidity which initiates the esterification reaction to selectively take place on γ position carboxyl group. In this autocatalytic process H2O has no effect on esterification. © 2014 Elsevier B.V. 
Esterification; L-glutamic acid; CuCl2; Autocatalytic process; Benzyl alcohol