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7955692 
Journal Article 
LUPIN ALKALOIDS .7. THE STRUCTURE OF ANGUSTIFOLINE, AN ALKALOID OF LUPINUS-ANGUSTIFOLIUS, IN SOLUTION 
Wysocka, W; Przybyl, A; Brukwicki, T 
1994 
Monatshefte fur Chemie / Chemical Monthly
ISSN: 0026-9247
EISSN: 1434-4475 
125 
11 
1267-1272 
English 
The1H and13C NMR spectra of the lupin alkaloid angustifoline1 in four solvents (cyclohexane-d12, CDCl3, CD3CN, and C6D6) were assigned using 2D H,H and H,C COSY and 2D J-resolved spectra. The torsional HCCH angles calculated from the vicinal JHH coupling constants are essentially in agreement with those expected for the deformed all-chair conformation with endo oriented N(12)-H bond, reported earlier for 1 in the solid state. Some arguments seem to point, however, to a small contribution of other conformations: with ring A deformed in another direction, deformed all-chair with exo oriented N(12)-H bond and/or a conformation with ring C in the boat form. 1994 Springer-Verlag. 
ANGUSTIFOLINE; CONFORMATION; NMR, QUINOLIZIDINE ALKALOIDS