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7987816 
Technical Report 
Practices, needs and methodologies for human exposure assessment at Cal/EPA: Report of the MMRA project team (Final interim report) 
Chan, D; Knadle, S; Painter, P; Randles, K; Salinas, J; Siegel, D 
2001 
California Environmental Protection Agency, Office of Environmental Health Hazard Assessment 
Sacramento, CA 
English 
The goal of the project is first to identify methodologies for predicting multimedia environmental fate and transport and to identify algorithms for all significant routes of exposure to environmental contaminants. The methodologies and algorithms that are consistent with the above RAAC recommendations and also are appropriate for use in the majority of human health risk assessments reviewed in programs in Cal/EPA will be recommended for inclusion in a model integrating multimedia fate and transport with human exposure assessment. One objective of the MMRA Project is to identify appropriate methodologies for predicting multimedia fate and transport of chemical contaminants. Tasks required to reach this objective are being performed by staff of the Department of Civil and Environmental Engineering at the University of California, Davis. Information from tasks focusing on fate and transport modeling is not contained in this report but is available in a separate report (Uddameri and Young, 1999). In 1998 the MMRA Project Team comprised of OEHHA staff with technical expertise in human health risk assessment was established to work toward the goal of the MMRA Project. In the same year, an Inter-Agency Work Group comprised of employees of the boards and departments of Cal/EPA and members of the MMRA Project Team was established to provide input on risk assessment practices and needs throughout Cal/EPA and to provide critical review of MMRA Project products. Two tasks to be completed during the first year of the project (Phase 1) were to identify both current uses and needs of Cal/EPA programs for exposure assessment methodologies and to identify documents on exposure assessment methodologies developed by U.S. government agencies, by California government agencies and by other organizations. A third task initiated during Phase 1 was the comparison of exposure algorithms recommended for use in several Cal/EPA programs. The following three chapters summarize the results of three distinct Phase 1 tasks. Chapter 2 discusses the survey of exposure assessment practices and perceived needs by the BDOs of Cal/EPA. Chapter 3 contains summaries of guidance documents used in risk assessments submitted to, or used by programs within the BDOs of Cal/EPA. This chapter also summarizes certain “leading edge” methodological approaches. Chapter 4 presents results of a task undertaken as a pilot project for a major Phase 2 task: the detailed comparison of exposure algorithms in three documents summarized in Chapter 3. The pilot project is a comparison of CalTOX; the Air Toxic “Hot Spots” or CAPCOA Guidelines; and Technical Support Document: Exposure Assessment and Stochastic Analysis (TSD/EASA) algorithms and procedures (OEHHA, 2000). Chapter 5 summarizes results of certain Phase 1 tasks and describes major Phase 2 tasks.