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8096554 
Journal Article 
PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITIES OF ARTEMISIA HERBA ALBA GROWN WILD IN ALTIB, IRAQ 
Aldhaher, AHS 
2021 
Connect Journal 
21 
1 
337-346 
English 
Artemisia herba alba has been used in modern and traditional medicine in different cultures over many years. The aim of present study was to explore the phytochemical composition, antibacterial and antifungal activity of various parts extracts of A. herba alba growing wild in Iraq. Methanol and water solvents were used to prepare leaves and roots extracts of A. herba alba and the essential oil was isolated by hydrodistillation and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). The antimicrobial activities were assayed by using well diffusion method against two bacteria Escherichia coli and Staphylococcus aureus and two fungus, Candida albicans and Aspergillus niger. Forty-three3 compounds have been identified from the essential oil of the plant, and 2,4-pentadiynylbenzene (27.33%), capillene (24.33%), 2-methylnaphthalene (8.52%) were the main constituents of the essential oil. Homoaromatic compounds with unsaturated hydrocarbon chain represented the main chemical class of the oil (52.75%) followed by sesquiterpens (10.58%) and fatty acids (4.85 %). The essential oil of A. herba alba showed strong antibacterial and antifungal activity in the range of 15-53 mm, whereas other extracts did not reveal antimicrobial activity. Thus, this study is the first chemical study of A. herba alba essential oil, growing wild in Iraq. It showed distinctive chemo style and effective essential oils against all microorganisms studied. © 2021. All Rights Reserved. 
antimicrobial; Artemisia herba alba; chemical constituent; essential oil