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HERO ID
8103481
Reference Type
Journal Article
Title
Total synthesis of the ubiquitin-activating enzyme inhibitor (+)-panepophenanthrin
Author(s)
Lei, X; Johnson, RP; Porco Jr., JA
Year
2003
Is Peer Reviewed?
Yes
Journal
Angewandte Chemie (International Edition)
ISSN:
1433-7851
EISSN:
1521-3773
Volume
42
Issue
33
Page Numbers
3913-3917
Language
English
DOI
10.1002/anie.200351862
Abstract
The [4+2] dimerization of epoxyquinol 1 is rendered irreversible by formation of a hemiacetal in the enantioselective total synthesis of the ubiquitin-activating enzyme inhibitor (+)-panepophenanthrin (2).
Keywords
Cycloaddition; Epoxyquinoids; Natural products; Total synthesis
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