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8105128 
Journal Article 
Isoquinoline alkaloids from Phoebe minutiflora 
Huang, FM; Huang, CF; Lee, SS 
1997 
49 
4 
217-227 
English 
This paper describes the chemical investigation of the alkaloids present in the stems and roots of Phoebe minutiflora. This study led to the characterization of fourteen isoquinolines via a combination of centrifugal partition chromatography as well as Sephadex LH-20 and conventional adsorption chromatography There are eight benzylisoquinolines- (-)-armepavine (1), (±)N-norarmepavine (2), (-)-N-methylisococlaurine (3), (-)-coclaurine (4), (+)-laudanidine (5), (+)-reticuline (6), (-)-norjuziphine (7) and (±)-juziphine (8), four aporphines-(+)-norisocorydine (9), (+)-isoboldine (10), (+)-corytuberine (11) and (+)-laurolitsine (12), one phenanthrene alkaloid-N-methylsecoglaucine (13), and one isoquinoline-O-methylcorypalline (14). Except for compounds 6, 8 and 12, the remaining compounds were isolated for the first time from Phoebe genus. Compound 13 is a novel natural product. This finding may be useful for the chemotaxonomy of Lauraceous plants. 
Aporphines; Benzylisoquinolines; Chemotaxonomy; CPC; Isoquinoline; Phoebe minutiflora